EVALUATION OF STERCULIA FOETIDA L. GUM AS NATURAL BASED CONTROLLED RELEASE EXCIPIENT

Vu Thi Hong Quan, Nguyen Thi Quan, Mai Thanh Phong, Le Thi Kim Phung

Abstract


Therefore, the physicochemical properties of Sterculia foetida L. gum, including solubility, scanning electron micrographs, melting point, swelling index, pH, viscosity, loss on drying were determined. Furthermore, compressed tablets were successfully prepared for in vitro studies at many different particle sizes, concentrations of gum, rotational speeds and media in order to evaluate the effects of these parameters on the rate of drug release. Besides, SFG tablets were compared with the tablets prepared with Hydroxymethylcellulose E15. The findings indicated that Sterculia foetida L. gum exhibited an excellent potential in managed release dosage forms. 


Keywords


Sterculia foetida L. gum, controlled release excipient, HPMC E15, in vitro release testing.

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References


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DOI: https://doi.org/10.15625/2525-2518/57/3/13323 Display counter: Abstract : 172 views. PDF : 42 views.

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