PHOTOTHERMAL EFFECT OF GOLD NANOSHELLS IN TISSUE

Vũ Thị Thùy Dương, Trịnh Thị Thương, Vũ Dương, Nguyễn Thị Thùy, Nghiêm Thị Hà Liên, Đỗ Quang Hòa, Trần Hồng Nhung

Abstract


This work presents the research results on photothermal effect caused by gold nanoshells Fe3O4/Si­O2/Au and Si­O2/Au in tissue under illumination of a diode laser continuous light at 808 nm. The results shown that the average temperature of samples injected with 1x108 Si­O2/Au and Fe3O4/Si­O2/Au nanoshells reach to 58° ± 5°C and 50° ± 5°C, respectively. This temperature can induce the irreversible damage to tissue. The photothermal transduction efficiency h of Fe3O4/Si­O2/Au and Si­O2/Au shells was determined as 16 % and 22 %, respectively. This study proves that gold nanoshells can be used to destroy the tumor cells by photothermal effect.

Keywords


hạt nano cấu trúc lõi/vỏ; hiệu ứng quang nhiệt



DOI: https://doi.org/10.15625/0866-708X/54/1/5814 Display counter: Abstract : 149 views. PDF (Tiếng Việt) : 461 views.

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Published by Vietnam Academy of Science and Technology