Antioxidant properties and total phenolic contents of various extracts from Houttuynia cordata Thunb

Phung Thi Tuyen, Do Tan Khang, Truong Thi Tu Anh, Pham Thanh Trang, Tran Dang Xuan


In this study, a comparative evaluation of total phenolic, total flavonoid, total tannin contents, and antioxidant activities of various extracts from Houttuynia cordata Thunb. (Saururaceae) was conducted. The solvents used in this study consisted of hexane, chloroform, acetonitrile, ethanol, methanol, and water. Results indicated that methanol extract possessed the highest total phenolic and total tannin contents (148.44 ± 12.81 mg gallic acid equivalent/g extract and 30.11 ± 0.48 mg catechin equivalent/g extract, respectively), while hexane extract presented the highest total flavonoid content (71.11 ± 6.76 mg rutin equivalent/g extract). Methanol extract showed the strongest antioxidant activities, followed by ethanol extract in DPPH (1,1-diphenyl-2-picrylhydrazyl), ABTS [2,2′-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid)], and reducing power methods. Gas chromatography-mass spectrometry analysis detected twenty-four components in methanol extract with n-decanoic acid; decanoic acid, methyl ester; 3H-pyrazol-3-one,2,4-dihydro-2,4,5-trimethyl-; 2-undecanone as the major compounds. In comparison among six types of solvents, methanol extract constituted a promising source of antioxidant compounds and it was the most potential solvent for extracting bioactive compounds of H. cordata.



Houttuynia cordata, antioxidant activity, gas chromatography-mass spectrometry, extracts, total phenolic content.

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